Africa has the assets to become an agriculture powerhouse: vast arable land, growing domestic markets, a maturing policy environment, and an upcoming demographic dividend. However, as many professionals developing agribusiness projects know, project development challenges often cause delays and cost overruns, which discourage greater long-term investments. Special Agricultural Processing Zones (SAPZ) are likely to ease many of these challenges, as is further work by governments and DFIs, such as the African Development Bank and the Development Finance Corporation to improve the infrastructure necessary to make private agro-industrial investments competitive and profitable. Unfortunately, the status quo remains that Africa receives some of the lowest amounts of FDI in the world, and among that, agricultural-related industries receive a tiny fraction. This dialogue is a frank conversation on what it would take to see greater involvement from the American private sector in the African agribusiness and begs a number of questions.