Many African countries have infrastructure deficits and numerous tax programs that often pose high negative impacts to operating of costs for trade, logistics and manufacturing activities. However, Special Economic Zones (SEZs) jurisdiction has shown great relief to companies operating within SEZs, with top level infrastructures, one-stop permits, duty waivers, efficient amenity services, supply chain logistics coordination etc. Attaining this height of efficiency by several SEZs across Africa remains at long vision. How can Africa change the game of SEZ development? What are the proven strategies for development of SEZs in Africa? What are the most efficient financing models for launching new SEZ?