Establishment of reliable transportation and energy infrastructure drove American economic & industrial dominance in the 20th century; renewal and expansion of that infrastructure is a focus of the bipartisan Infrastructure and Jobs Act signed into law by President Biden in November 2021. The need for continued investment in Africa’s transportation, energy, communications, and other core infrastructure is likewise needed to drive rapid growth on a continent full of potential. To address the global infrastructure gap, the Biden Administration launched the Partnership for Global Infrastructure and Investment (PGI), including expanding the Lobito Corridor in partnership with the governments of Angola, the Democratic Republic of the Congo, Zambia, and other partners. Highlighting the transformational role of strategic investment and partnership in the infrastructure sector across the continent will be the focus of this session.