By the end of this century, more than half of the world's population growth is expected to come from Africa, reaching more than 4 billion people. At present, the African continent holds a significant challenge of food security and resilience while at the same time has 60% of the world’s uncultivated arable land. In time, Africa can reshape its food future through a coherent, strategic, and pragmatic approach to support entrepreneurship and technology in the agribusiness sector. To do so effectively it needs expertise, technology access and partnerships. The U.S. agriculture sector is one of the largest and most productive in the world, possessing incredible resources and expertise. However, the U.S. agro-industrial sector is almost entirely built out, thus reliant upon new markets for growth. This high-level dialogue seeks to build a compelling case for resilient strategic partnership to strengthen U.S.-Africa agribusiness partnerships. It aims to showcase impactful examples of successful U.S.-Africa agribusiness investments, providing concrete proof of the potential for growth and collaboration. Additionally, the dialogue will analyze the trajectory ahead, identifying both challenges to overcome and opportunities to be seized.